bio-applied-data-harmonization

SKILLWorkflowcommunity
v0.0.0Pavel-KravchenkoUnknownUpdated 1mo agoSource →

Harmonize multi-omics data (RNA-seq, proteomics, methylation, metabolomics) before integration — per-layer normalization, KNN/half-minimum missing-value imputation, PCA/PVCA batch-effect detection, and ComBat correction with pandas/scikit-learn. Use when prepping matrices for MOFA2/DIABLO/mixOmics,

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1mo agoLast update
Skill
AuthorPavel-Kravchenko
Version0.0.0
LicenseUnknown
CategoryWorkflow
Formatsskill.md
PromptNot published
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Claude✓ Supported
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Harmonize multi-omics data (RNA-seq, proteomics, methylation, metabolomics) before integration — per-layer normalization, KNN/half-minimum missing-value imputation, PCA/PVCA batch-effect detection, and ComBat correction with pandas/scikit-learn. Use when prepping matrices for MOFA2/DIABLO/mixOmics, fixing missing values in proteomics MS data, or removing batch effects confounded with sequencing da

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