Call DMRs from WGBS/RRBS beta values via BSmooth smoothing/t-stats or DSS/methylKit (R); annotate to promoters/CpG islands, correlate with RNA-seq log2FC. Use for DMR calling, DSS callDMR, or methylation-expression integration.
Call DMRs from WGBS/RRBS beta values via BSmooth smoothing/t-stats or DSS/methylKit (R); annotate to promoters/CpG islands, correlate with RNA-seq log2FC. Use for DMR calling, DSS callDMR, or methylation-expression integration.