bio-applied-metabolic-flux

SKILLWorkflowcommunity
v0.0.0Pavel-KravchenkoUnknownUpdated 1mo agoSource →

Run flux balance analysis (FBA/FVA) on genome-scale metabolic models (E. coli core, Recon3D, AGORA2) with COBRApy; simulate single/double gene knockouts and integrate RNA-seq expression via GIMME/iMAT. Use when predicting metabolic fluxes, finding essential genes or drug targets, doing synthetic let

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1mo agoLast update
Skill
AuthorPavel-Kravchenko
Version0.0.0
LicenseUnknown
CategoryWorkflow
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Run flux balance analysis (FBA/FVA) on genome-scale metabolic models (E. coli core, Recon3D, AGORA2) with COBRApy; simulate single/double gene knockouts and integrate RNA-seq expression via GIMME/iMAT. Use when predicting metabolic fluxes, finding essential genes or drug targets, doing synthetic lethality screens, or building transcriptomics-constrained metabolic models from SBML/JSON GEMs.

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skillclaude