Find ChIP-seq/ATAC-seq peaks that gain or lose signal between conditions using DiffBind (dba.count/dba.normalize/dba.analyze with DESeq2 or edgeR) on a consensus peak set, then annotate hits to genes/promoters with ChIPseeker annotatePeak. Use when comparing TF binding or histone marks across condit
Find ChIP-seq/ATAC-seq peaks that gain or lose signal between conditions using DiffBind (dba.count/dba.normalize/dba.analyze with DESeq2 or edgeR) on a consensus peak set, then annotate hits to genes/promoters with ChIPseeker annotatePeak. Use when comparing TF binding or histone marks across conditions, building volcano/MA plots from dba.report() output, or annotating differential peaks to neares