bio-applied-differential-binding

SKILLWorkflowcommunity
v0.0.0Pavel-KravchenkoUnknownUpdated 1mo agoSource →

Find ChIP-seq/ATAC-seq peaks that gain or lose signal between conditions using DiffBind (dba.count/dba.normalize/dba.analyze with DESeq2 or edgeR) on a consensus peak set, then annotate hits to genes/promoters with ChIPseeker annotatePeak. Use when comparing TF binding or histone marks across condit

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1mo agoLast update
Skill
AuthorPavel-Kravchenko
Version0.0.0
LicenseUnknown
CategoryWorkflow
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Find ChIP-seq/ATAC-seq peaks that gain or lose signal between conditions using DiffBind (dba.count/dba.normalize/dba.analyze with DESeq2 or edgeR) on a consensus peak set, then annotate hits to genes/promoters with ChIPseeker annotatePeak. Use when comparing TF binding or histone marks across conditions, building volcano/MA plots from dba.report() output, or annotating differential peaks to neares

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