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Every entry, alphabetically — 77,915 in total. Page 49 of 312.

• better-stack-api-patternsBetter Stack MCP and API surface across Uptime, Telemetry (Logtail), and Error Tracking: available tools, Bear
• better-stack-automationAutomate Better Stack tasks via Rube MCP (Composio). Always search tools first for current schemas.
• better-stack-incidentsBetter Stack incidents: incident records raised by uptime monitors or reported manually, and the triage, ackno
• better-stack-loggingBetter Stack log management (Logtail): log sources, structured log search and query syntax, log-based alerting
• better-stack-monitorsBetter Stack uptime monitors: check types, monitor fields, heartbeat monitors, monitor groups, and create/upda
• better-stack-on-callBetter Stack on-call: on-call calendars and rotations, escalation and notification policies, alert routing, an
• better-stack-status-pagesBetter Stack status pages: status page configuration, resources and components, maintenance windows, and publi
• better-telegram-mcpTelegram for AI agents: messages, chats, media, and contacts in bot and user-account modes.
• bettercallzaal-fix-issueUse when fixing a GitHub issue — reads the issue, implements the fix, writes tests, and commits referencing th
• bettermemoryMemory for coding agents, checked against the filesystem and git before it is believed.
• betterstackEvery Better Stack Uptime feature, plus an offline SQLite mirror and cross-resource fleet analytics - what's
• between-runs-auditUse between coding-agent runs (Codex, Claude Code, Cursor, Aider, etc.) to stop the project from drifting, ove
• bevigil-mcp-serverDiscover mobile app attack surfaces via BeVigil OSINT — hosts, subdomains, URLs, and more.
• bevy-ecsStructure a Bevy app around its Entity Component System: build the App with plugins, define Component/Resource
• beweislast-und-zugang-309Wenn es um Beweislast und Zugang 309 in AGB-Recht-Prüfer geht: zerlegt Ergebnis, Frist, Zuständigkeit, Beweisl
• bewertung-rezensionenWenn es um Bewertung Rezensionen in AGB-Recht-Prüfer geht: ordnet Sachverhalt, Norm, Beweislast, Gegenargument
• beyond-the-wrapperPosition an AI product when everyone claims AI and skeptics call it \"just a wrapper.\" Find the real wedge (d
• beyondkmp/claude-code-pluginsclaude-code-plugins
• bfsg-anwendungsbereichAnwendungsbereich des Barrierefreiheitsstärkungsgesetzes – abschließender Produktkatalog § 1 Abs. 2 BFSG und D
• bfsg-dienstleistung-ecommerceBarrierefreiheit von Dienstleistungen im elektronischen Geschäftsverkehr – Pflichten des Dienstleistungserbrin
• bfsg-produktkonformitaetProduktkonformität nach dem BFSG – Herstellerpflichten § 6 mit technischer Dokumentation nach Anlage 2, Konfor
• bg-removerBackground removal utility — image in, transparent PNG out. Wraps Replicate-hosted models (851-labs/background
• bg-szy-brainstormingInteractive idea refinement using Socratic method to develop fully-formed designs
• bg-szy-canvas-designDesign philosophy docs and canvas-based visual creation. Use when articulating design principles, crafting mul
• bg-szy-codebase-designShared vocabulary for designing deep modules. Use when the user wants to design or improve a module's interfac
• bg-szy-context-mapScope the real change surface before editing. Use when planning a feature, bugfix, refactor, or review and you
• bg-szy-docUse when the task involves reading, creating, or editing `.docx` documents, especially when formatting or layo
• bg-szy-docxUse this skill whenever the user wants to create, read, edit, or manipulate Word documents (.docx files). Cove
• bg-szy-frontend-designDesign and implement context-fit frontend interfaces with deliberate art direction, accessible interaction, re
• bg-szy-handoffCompact the current conversation into a handoff document for another agent to pick up.
• bg-szy-improve-codebase-architectureScan a codebase for deepening opportunities, present them as a visual HTML report, then guide a user-directed
• bg-szy-mcp-builderBuild high-quality MCP servers with strong tool design, structured outputs, clear error handling, and realisti
• bg-szy-pdfUse when tasks involve reading, creating, or reviewing PDF files where rendering and layout matter; prefer vis
• bg-szy-pptxUse this skill any time a `.pptx` file is involved as input, output, or both. Covers reading decks, editing ex
• bg-szy-prototypeBuild a throwaway prototype to answer a design question. Use when the user wants to sanity-check whether a sta
• bg.namerimidom/namerimidomSearch homes for sale and rent in Bulgaria; get price stats and alerts for new matches.
• bgpt-paper-searchSearch scientific papers and retrieve structured experimental data extracted from full-text studies via the BG
• bhala-srinivash-learnCognitive science-based AI tutor that won't let you fake understanding. Implements a full teaching loop (Expla
• bhancockio/agent2agent
• bharatlas-mcpQuery India's open geo data, and author collect maps: register a link, moderate, publish.
• bhived-mcpBhived MCP Server — shared knowledge graph for AI agents. Query, write, and inspect collective AI knowledge th
• bhoon716-bugfixUse when the user asks to diagnose and fix broken, incorrect, failing, flaky, or regressed behavior, such as f
• bhoon716-refactoringUse when the user asks to refactor, clean up, simplify, extract, rename, remove duplication, improve readabili
• bhoonidhi-mcpSearch, save, and download satellite scenes from ISRO's Bhoonidhi portal in natural language.
• bias-assessorUse when `evidence-review` has an extraction table and needs lightweight risk-of-bias fields. **Trigger**: bia
• bias-detection-mcpAI bias detection and fairness assessment for AI agents. Instant bias risk scan, demographic ana...
• bias-detectorDetect cognitive and statistical biases — confirmation bias, survivorship bias, sampling issues, and logical f
• bib-verifyVerify a BibTeX file for hallucinated or fabricated references by cross-checking every entry against CrossRef,
• bible.vineverse/vineverseBible knowledge graph: 31,102 verses, 341,289 cross references, people, places, themes.
• bible.void/readerRead it the way a person does: one fragment at a time. If the same words return, you asked too soon.
• bibtexConventions for creating and editing BibTeX entries. Use when adding references to .bib files or converting in
• bibverifyVerify and repair BibTeX references with DOI-first MCP tools.
• bid-analysis-comparatorCompare and analyze contractor bids. Score proposals, identify scope gaps, and recommend selections.
• bid-evaluatorEvaluate tabulated subcontractor bids against specs and drawings — scope gap analysis, exclusion risk scoring,
• bid-strategy-plannerUse when the user asks to "pick a bid strategy", "set a tCPA/tROAS target", or "plan the learning-phase entry"
• bid-tabulatorExtract data from subcontractor bid PDFs and produce a comparison spreadsheet. Feeds into /bid-evaluator. Trig
• bid-tender-reviewAnalyse a construction bid or tender package for scope gaps, risk-shifting exclusions, unit-rate red flags, an
• bid.scope/healthcareHealthcare vendor-services MCP. Preview. Available after legal, claims, and AEC are live.
• bid.scope/pharmaPharma vendor-services MCP. Preview. Available after legal, claims, and AEC are live.
• bidsUse this skill when working with Brain Imaging Data Structure (BIDS) datasets: organizing neuroscience and bio
• bidsketch-automationAutomate Bidsketch tasks via Rube MCP (Composio). Always search tools first for current schemas.
• big-data-cloud-automationAutomate Big Data Cloud tasks via Rube MCP (Composio). Always search tools first for current schemas.
• big-purchase-decisionEvaluates a major purchase with total cost of ownership, opportunity cost, affordability red lines, and a cool
• big-purchase-timingDecide when to buy a big-ticket item to get the best price — the sales cycles, model-refresh timing, and 'buy
• bigbrownjeff-project-initSeed a new project's Claude context at the START — scaffold a tight CLAUDE.md (stack, constraints, run/test/de
• bigcommerce-webhooksReceive and verify BigCommerce webhooks. Use when setting up BigCommerce webhook handlers, debugging Standard
• biggishExplains the migration procedure in depth. Use when the user runs a data migration or mentions migration steps
• biggora/claude-plugins-registryCLI marketplace for discovering, installing, and managing Claude Code plugins.
• bighardperson-agent-browserA fast Rust-based headless browser automation CLI with Node.js fallback that enables AI agents to navigate, cl
• bighardperson-algorithmic-artCreating algorithmic art using p5.js with seeded randomness and interactive parameter exploration. Use this wh
• bighardperson-deep-researchStructured deep research workflow with human-in-the-loop control. Use /research to generate research outline,
• bighardperson-llm-wikiBuild and maintain a personal knowledge base (wiki) using LLMs. Instead of RAG-style retrieval, the LLM increm
• bighardperson-mcp-builderGuide for creating high-quality MCP (Model Context Protocol) servers that enable LLMs to interact with externa
• bighardperson-research对目标话题进行初步调研，生成调研outline。用于学术调研、benchmark调研、技术选型等场景。
• bigmailer-automationAutomate Bigmailer tasks via Rube MCP (Composio). Always search tools first for current schemas.
• bigml-automationAutomate Bigml tasks via Rube MCP (Composio). Always search tools first for current schemas.
• bigpapicb-code-reviewSystematic code review checklist covering correctness, security, performance, and maintainability. Use when re
• bigpapicb-debuggingSystematic diagnostic strategy with decision tree for reproducing, isolating, and tracing bugs. Use when inves
• bigpapicb-mcp-builderBuild MCP (Model Context Protocol) servers in TypeScript or Python. Use when creating custom tools, resources,
• bigpapicb-refactoringWhen to refactor vs leave alone, code smell detection, safe refactoring steps, and common transformation patte
• bigpapicb-researchStructured research methodology with scoping, multi-source collection, triangulation, source credibility scori
• bigpapicb-security-auditSecurity audit with OWASP top 10 checklist, dependency scanning, secrets detection, input validation, and inje
• bigqueryGoogle BigQuery for analytics, ML, and data warehousing. Use for large-scale analytics.
• bigquery-ai-mlSkill for BigQuery AI and Machine Learning queries using standard SQL and `AI.*` functions (preferred over ded
• bigquery-analyticsUse these skills when you need to handle advanced data intelligence and predictive tasks. Use when a user asks
• bigquery-cost-auditUse when reviewing BigQuery spend, query failure patterns, or scan inefficiencies -- identifying which jobs, u
• bigquery-cost-optimizationUse when asking about BigQuery costs, pricing, bytes billed, slot usage, reducing query costs, choosing betwee
• bigquery-dataUse these skills when you need to handle large-scale data exploration and dataset management. Use when users n
• bigquery-featuresUse when asking about BigQuery-specific features, syntax, or capabilities including: STRUCT/ARRAY/UNNEST patte
• bigquery-optimizationUse when writing, reviewing, or optimizing BigQuery SQL, asking about BigQuery best practices, working with .s
• bigquery-pipeline-auditAudits Python + BigQuery pipelines for cost safety, idempotency, and production readiness. Returns a structure
• bigquery-query-generationUse when generating BigQuery SQL from natural language descriptions, converting queries from other SQL dialect
• bigquery-schema-designUse when designing BigQuery table schemas, choosing partitioning or clustering strategies, deciding between ne
• biii-mcpFail-closed safe-to-pay verdicts on Base: known-bad wallets, look-alike tokens, repeat rug funders.
• bikeshedDemocratic technical discussion. Use in design reviews and RFC threads to make sure every voice is heard on th
• bilal140202-artifacts-builderSuite of tools for creating elaborate, multi-component claude.ai HTML artifacts using modern frontend web tech
• bilal140202-frontend-designCreate distinctive, production-grade frontend interfaces with high design quality. Use this skill when the use
• bilal140202-frontend-slidesCreate stunning, animation-rich HTML presentations from scratch or by converting PowerPoint files. Use when th
• bilal140202-postgresqlDesign a PostgreSQL-specific schema. Covers best-practices, data types, indexing, constraints, performance pat
• bilal140202-skill-creatorGuide for creating effective skills. This skill should be used when users want to create a new skill (or updat
• bildungs-kurs-agbWenn es um Bildungs Kurs AGB in AGB-Recht-Prüfer geht: ordnet Sachverhalt, Norm, Beweislast, Gegenargumente un
• bilibili-audio下载B站视频音频。支持单个视频下载和批量下载UP主所有视频。当用户提供B站视频链接（bilibili.com、b23.tv）、要求下载B站音频、下载B站视频、提取B站音频、或批量下载某个UP主的视频时使用。触发词：B站下
• bilibili-page-readerGet content from Bilibili videos: official subtitles, danmaku (density/peaks/sample), comments. When no subtit
• bilibili-proBilibili（B 站）公开数据查询与内容分析 skill，通过 MaxHub API 查询视频详情、播放信息、字幕、分 P、BV/AV 转换、UP 主资料、投稿、动态、搜索、热搜、评论弹幕、直播间与公开收藏夹等 40
• bilibili-transcribe哔哩哔哩视频 → 下载 → 转录 → 存为 Markdown 的完整工作流。 支持 BV 号和完整链接，无需登录。
• bilig-workpaperFormula WorkPaper runtime and MCP server for AI agents and Node.js services. Use when an agent needs spreadshe
• bilincHosted agent memory with provenance, contradiction surfacing, and snapshot rollback.
• bilingual-doc-sync>
• bill-debate-traceTrace the parliamentary journey of a UK bill — debates, key contributions, and divisions. Use whenever the use
• bill-gatesBill Gates - Tecnologia, pensamento sistêmico e filantropia estratégica
• billable-time-stephane-boghossianWhen your bar comes asking "show me how you billed AI-assisted work" — and ABA 512, Florida 24-1, California,
• billing-automationBuild automated billing systems for recurring payments, invoicing, subscription lifecycle, and dunning managem
• billing-cycle-manager-scott-margettsOperational billing execution for legal matters. Monthly bill prep and billing instructions, LC invoice review
• billing-doctorDiagnose Google Play Billing incidents locally, with evidence. Not affiliated with Google.
• billy-enrizky-deep-researchConduct deep web research using the openbrowser-ai agent: decompose a query, investigate sub-questions across
• billy-enrizky-web-scrapingExtract structured data from websites, scrape page content, and collect information across multiple pages. Tri
• billy-mcpMCP server for Billy (billy.dk) accounting — connect Claude and other AI assistants to your Danish bookkeeping
• biltSearch Bilt Rewards travel portal for cash and Bilt Points pricing on hotels and flights. Public REST API, no
• bim-clash-detectionDetect and analyze geometric clashes in BIM models. Identify MEP, structural, and architectural conflicts befo
• bim-classification-aiClassify BIM elements using AI and standard classification systems. Map elements to UniFormat, MasterFormat, O
• bim-cost-estimation-cwicrAutomated cost estimation from BIM models using DDC CWICR database with 55,719 work items. AI classification +
• bim-to-schedule-4dCreate 4D construction simulations by linking BIM models with project schedules.
• bim-validation-reportGenerate comprehensive BIM model validation reports. Check data quality, completeness, and compliance with sta
• bima-mcp🛡️ bima-mcp — Kenya Insurance Intelligence MCP Server
• binance-pricesFetch cryptocurrency prices from Binance public API (no API key required). Use when user asks for BTC, ETH, SO
• binance-square币安广场合约投机雷达 v5：以最近24小时专业交易帖为主要证据，回源核验帖子， 联合币安公共合约行情、4周期K线、布林带、ATR、量能和RR，生成可审计的本地影子报告。 触发词：币安广场、扫描币安、binance squ
• binance-trendingAn installable, cross-framework AI organization: C-suite agents, expert subagents, curated skills, independent
• binary-analysisAnalyze unknown binary files through a deterministic CLI that wraps Ghidra's static-analysis engine. Use when
• binary-analysis-patternsMaster binary analysis patterns including disassembly, decompilation, control flow analysis, and code pattern
• bind-alias-mcpMCP bridge for BindAlias Minecraft mod: game state, screenshots, aliases, and config editing.
• bind-alias-plus-mcpMCP stdio bridge for the BindAliasPlus Minecraft mod — query game state, take screenshots, execute aliases, an
• bindcraftEnd-to-end binder design using BindCraft hallucination. Use this skill when: (1) Designing protein binders wit
• binder-designGuidance for choosing the right protein binder design tool. Use this skill when: (1) Deciding between BoltzGen
• binder-design-campaign-managerBinder design campaign planning, monitoring, and troubleshooting. Use this skill when: (1) Planning a complete
• binder-design-tool-selectionBinder design tool selection and workflow routing guidance. Use this skill when: (1) Deciding between BoltzGen
• binding-characterizationGuidance for SPR and BLI binding characterization experiments. Use when: (1) Planning binding kinetics experim
• bindingdb-databaseQuery BindingDB for measured drug-target binding affinities (Ki, Kd, IC50, EC50). Search by target (UniProt ID
• binkyIsolated dev environments, one per git worktree: ports, env, and DB slices as agent tools.
• binlog-failure-analysisAnalyze MSBuild binary logs to diagnose build failures. USE FOR: build errors that are unclear from console ou
• binlog-generationGenerate MSBuild binary logs (binlogs) for build diagnostics and analysis. USE FOR: adding /bl:{} to any dotne
• bio-admet-predictionPredicts ADMET properties using ADMETlab 3.0 API or DeepChem models. Estimates bioavailability, CYP inhibition
• bio-agent-skills-hubDiscover and invoke 1,676 deduplicated biomedical AI agent skills from the Awesome Bio Agent Skills repository
• bio-alignment-files-bam-statisticsThe largest open-source medical AI skills library for OpenClaw🦞.
• bio-alignment-filteringThe largest open-source medical AI skills library for OpenClaw🦞.
• bio-alignment-indexingThe largest open-source medical AI skills library for OpenClaw🦞.
• bio-alignment-ioRead, write, and convert multiple sequence alignment files using Biopython Bio.AlignIO. Supports Clustal, PHYL
• bio-alignment-msa-parsingParse and analyze multiple sequence alignments using Biopython. Extract sequences, identify conserved regions,
• bio-alignment-msa-statisticsCalculate alignment statistics including sequence identity, conservation scores, substitution matrices, and si
• bio-alignment-pairwisePerform pairwise sequence alignment using Biopython Bio.Align.PairwiseAligner. Use when comparing two sequence
• bio-alignment-sortingThe largest open-source medical AI skills library for OpenClaw🦞.
• bio-alignment-validationThe largest open-source medical AI skills library for OpenClaw🦞.
• bio-analysis-systemA curated collection of AI agent skills for biomedical research, covering genomics, proteomics, single-cell an
• bio-applied-advanced-ngsAssemble genomes de novo: greedy OLC, de Bruijn graph/Eulerian path, N50/L50/NG50 stats, SPAdes/Flye/hifiasm C
• bio-applied-assembly-binningAssemble shotgun metagenomic reads with MEGAHIT, bin contigs with MetaBAT2/CONCOCT/MaxBin2+DAS_Tool, grade MAG
• bio-applied-assembly-svAssemble ONT/HiFi reads with Flye/Hifiasm, polish with Medaka, QC with QUAST/BUSCO, call SVs (DEL/INS/INV/DUP/
• bio-applied-bayesian-statistics-pythonFit Bayesian models with PyMC/Bambi/ArviZ: NUTS sampling, prior/posterior checks, HDI intervals, hierarchical
• bio-applied-bio-data-formatsParse/write FASTA, FASTQ, SAM/BAM, VCF, BED, GFF/GTF with pysam and pure Python; decode SAM FLAG/CIGAR; reconc
• bio-applied-biochemistryFit Michaelis-Menten Vmax/Km with scipy curve_fit, convert absorbance to concentration via Beer-Lambert, and m
• bio-applied-cancer-transcriptomicsClassify tumor RNA-seq into subtypes (melanoma Tirosh/Harbst on TCGA-SKCM): log1p/z-score, PCA/t-SNE, hierarch
• bio-applied-capstone-projectBLAST-identify unknown DNA/CDS with Biopython, QC/translate sequences, build NJ/UPGMA trees, and scan protein
• bio-applied-cell-type-annotationAnnotate scRNA-seq Leiden/Louvain clusters into cell types via canonical marker scoring, SingleR reference cor
• bio-applied-chipseq-pipelineFASTQ-to-peaks ChIP-seq pipeline: Bowtie2 align, Picard dedup, MACS2/MACS3 narrow/broad peak calling, FRiP/IDR
• bio-applied-cite-seq-integrationNormalize CITE-seq ADT counts (CLR/DSB) and build WNN graphs joining RNA+protein or RNA+ATAC with muon/Seurat
• bio-applied-clinical-genomicsClassify germline variant pathogenicity with ACMG/AMP 5-tier criteria (PVS1/PS1-4/PM1-6/PP1-5/BA1/BS1-4/BP1-7)
• bio-applied-copy-number-analysisCall CNVs from binned read-depth: GC-bias normalization, circular binary segmentation (CBS), log2-ratio-to-CN-
• bio-applied-coverage-tracksGenerate normalized bigWig coverage tracks from BAM with deepTools bamCoverage/bamCompare (RPKM/CPM/RPGC), sum
• bio-applied-data-harmonizationHarmonize multi-omics data (RNA-seq, proteomics, methylation, metabolomics) before integration — per-layer nor
• bio-applied-deep-learning-for-biologyTrain PyTorch CNN/LSTM/Transformer/VAE on DNA/protein sequences: one-hot encoding, motif filters, saliency. Us
• bio-applied-differential-bindingFind ChIP-seq/ATAC-seq peaks that gain or lose signal between conditions using DiffBind (dba.count/dba.normali
• bio-applied-dimensionality-reductionCompute PCA/UMAP embeddings and Leiden clusters for scRNA-seq with scanpy/Seurat; tune n_pcs/n_neighbors/resol
• bio-applied-dmr-analysisCall DMRs from WGBS/RRBS beta values via BSmooth smoothing/t-stats or DSS/methylKit (R); annotate to promoters
• bio-applied-dockingDock ligands into a receptor with AutoDock Vina: build PDBQT files (Open Babel/RDKit), set the grid box, run v
• bio-applied-enzyme-kineticsFit Michaelis-Menten/Hill kinetics with scipy curve_fit; get Vmax/Km/kcat with bootstrap CIs, classify enzyme
• bio-applied-epigenetic-clocksCompute DNA methylation age (Horvath/Hannum/GrimAge/PhenoAge elastic-net clocks) from 450K/EPIC beta values an
• bio-applied-flow-cytometryRead FCS 2.0/3.0/3.1 files with FlowKit/flowio, apply spillover compensation, logicle/arcsinh transforms, buil
• bio-applied-functional-annotationProfile MetaCyc pathways/genes from metagenomes with HUMAnN3, test differential abundance via MaAsLin2, detect
• bio-applied-gene-regulatory-networksInfer TF-target regulatory networks via correlation, ARACNE mutual information, and GENIE3 random-forest impor
• bio-applied-genetic-engineering-in-silicoSimulate restriction digests, overhang compatibility, and primer Tm (Wallace/SantaLucia NN) in Python; plot ag
• bio-applied-genome-assemblyImplement OLC and de Bruijn assembly algorithms, compute N50/L50/NG50 stats, and run SPAdes/Flye/hifiasm on Il
• bio-applied-gwasRun GWAS: SNP QC (MAF/HWE), PCA ancestry covariates, per-SNP logistic/linear regression, Manhattan/QQ plots, g
• bio-applied-hla-typingType HLA-A/B/C/DRB1 with OptiType/arcasHLA and predict peptide-MHC binding (NetMHCpan %Rank_EL/IC50) to rank n
• bio-applied-immune-repertoireAnalyze TCR/BCR repertoires with scirpy: import MiXCR/10x/AIRR clonotypes, define clonotypes, compute clonal e
• bio-applied-isoform-analysisAlign ONT/PacBio long reads with Minimap2 splice, call isoforms with bambu (NDR), test differential isoform us
• bio-applied-lc-ms-preprocessingPreprocess raw LC-MS mzML with XCMS centWave peak picking, obiwarp RT alignment, gap filling, PQN/QC normaliza
• bio-applied-lncrna-classificationClassify StringTie/gffcompare transcripts into lncRNA subtypes by class code/length/TPM, score coding potentia
• bio-applied-machine-learning-for-biologyEngineer k-mer/GC/CpG DNA features, train scikit-learn classifiers (LogisticRegression, RandomForest, SVC), ev
• bio-applied-mageck-gene-essentialityRun MAGeCK count/test on pooled CRISPR sgRNA screens, scoring gene essentiality via RRA, FDR, and log2 fold-ch
• bio-applied-metabolic-fluxRun flux balance analysis (FBA/FVA) on genome-scale metabolic models (E. coli core, Recon3D, AGORA2) with COBR
• bio-applied-metabolite-identificationAssign molecular formulas from accurate mass/adducts and match MS/MS spectra by cosine similarity to GNPS/Mass
• bio-applied-microbial-diversityCompute alpha/beta diversity (Shannon, Simpson, Bray-Curtis, UniFrac) from a 16S/ASV feature table with scikit
• bio-applied-mirna-seq-pipelineTrim adapters (cutadapt), align to miRBase with Bowtie, quantify with featureCounts, run DESeq2/CPM DE testing
• bio-applied-mixomicsRun mixOmics PLS-DA/sPLS-DA/DIABLO to classify samples and pick stable biomarkers from paired RNA-seq/proteomi
• bio-applied-mofa2Run MOFA2 (mofapy2/muon) to fuse RNA-seq, proteomics, methylation into latent factors; decompose per-view R2,
• bio-applied-molecular-evolutionTest Hardy-Weinberg equilibrium, simulate Wright-Fisher drift/selection, and compute dN/dS, Tajima's D, and Fs
• bio-applied-molecular-gnnTrain PyTorch Geometric GCN/MPNN on SMILES-derived molecular graphs to predict properties (BBBP, solubility, t
• bio-applied-molecular-modelingCompute force-field energy terms (bond/LJ/Coulomb), run energy minimization, and QC MD/homology models (RMSD,
• bio-applied-network-modulesDetect PPI/co-expression modules with NetworkX/python-louvain/leidenalg (Louvain, Leiden, modularity Q) and WG
• bio-applied-ngs-fundamentalsDecode Phred+33 FASTQ quality scores, compute FastQC-style per-position QC stats, and sliding-window trim read
• bio-applied-numerical-methods-for-bioinformaticsInterpolate missing time points (Newton/cubic spline), estimate derivatives, and compute AUC via trapezoidal/S
• bio-applied-ont-processingBasecall ONT POD5/FAST5 signal with Dorado (fast/hac/sup, duplex, 5mC/5hmC), QC with NanoStat/NanoPlot, filter
• bio-applied-phylodynamicsBuild time-scaled phylogenies with TreeTime/Augur, validate clock via root-to-tip regression, interpret BEAST2
• bio-applied-population-geneticsTest Hardy-Weinberg equilibrium, simulate Wright-Fisher drift/selection, and compute dN/dS, Tajima's D, Fst, L
• bio-applied-ppi-networksBuild and analyze protein-protein interaction (PPI) networks from STRING DB with NetworkX: compute degree/betw
• bio-applied-primer-designDesign PCR/qPCR primers with primer3-py design_primers/calc_hairpin, Bio.SeqUtils Tm, and blastn specificity c
• bio-applied-promoterDetect TATA box/Inr/DPE promoter elements, call CpG islands (O/E ratio), and build/score PWMs for TFBS scannin
• bio-applied-proteomicsCompute peptide b/y ion masses, run trypsin/PMF search, quantify LFQ protein abundance (volcano plots), and ca
• bio-applied-qiime2-16sRun QIIME2 16S amplicon workflows: import FASTQ, DADA2 denoise to ASVs, SILVA taxonomy, alpha/beta diversity,
• bio-atac-seq-atac-peak-callingCall accessible chromatin regions from ATAC-seq data using MACS3 with ATAC-specific parameters. Use when ident
• bio-atac-seq-atac-qcQuality control metrics for ATAC-seq data including fragment size distribution, TSS enrichment, FRiP, and libr
• bio-atac-seq-differential-accessibilityFind differentially accessible chromatin regions between conditions using DiffBind or DESeq2. Use when compari
• bio-atac-seq-footprintingDetect transcription factor binding sites through footprinting analysis in ATAC-seq data using TOBIAS. Use whe
• bio-atac-seq-motif-deviationAnalyze transcription factor motif accessibility variability using chromVAR. Use when identifying which TF mot
• bio-atac-seq-nucleosome-positioningExtract nucleosome positions from ATAC-seq data using NucleoATAC, ATACseqQC, and fragment analysis. Use when a
• bio-basecallingConvert raw Nanopore signal data (FAST5/POD5) to nucleotide sequences using Dorado basecaller. Covers model se
• bio-batch-downloadsThe largest open-source medical AI skills library for OpenClaw🦞.
• bio-batch-processingProcess multiple sequence files in batch using Biopython. Use when working with many files, merging/splitting
• bio-bedgraph-handlingThe largest open-source medical AI skills library for OpenClaw🦞.
• bio-blast-searchesThe largest open-source medical AI skills library for OpenClaw🦞.
• bio-causal-genomics-colocalization-analysisTest whether two traits share a causal variant at a genomic locus using Bayesian colocalization with coloc. Co
• bio-causal-genomics-fine-mappingIdentify likely causal variants within GWAS loci using SuSiE for sum of single effects regression and FINEMAP
• bio-causal-genomics-mediation-analysisDecompose genetic effects into direct and indirect paths through mediating variables using the mediation R pac
• bio-causal-genomics-mendelian-randomizationEstimate causal effects between exposures and outcomes using genetic variants as instrumental variables with T
• bio-causal-genomics-pleiotropy-detectionDetect and correct for horizontal pleiotropy in Mendelian randomization analyses using MR-PRESSO for outlier r
• bio-cfdna-preprocessingPreprocesses cell-free DNA sequencing data including adapter trimming, alignment optimized for short fragments
• bio-chipseq-differential-bindingDifferential binding analysis using DiffBind. Compare ChIP-seq peaks between conditions with statistical rigor
• bio-chipseq-motif-analysisDe novo motif discovery and known motif enrichment analysis using HOMER and MEME-ChIP. Identify transcription
• bio-chipseq-peak-annotationAnnotate ChIP-seq peaks to genomic features and genes using ChIPseeker. Assign peaks to promoters, exons, intr
• bio-chipseq-peak-callingChIP-seq peak calling using MACS3 (or MACS2). Call narrow peaks for transcription factors or broad peaks for h
• bio-chipseq-qcChIP-seq quality control metrics including FRiP (Fraction of Reads in Peaks), cross-correlation analysis (NSC/
• bio-chipseq-super-enhancersIdentifies super-enhancers from H3K27ac ChIP-seq data using ROSE and related tools. Use when studying cell ide
• bio-chipseq-visualizationVisualize ChIP-seq data using deepTools, Gviz, and ChIPseeker. Create heatmaps, profile plots, and genome brow
• bio-clinical-databases-clinvar-lookupQuery ClinVar for variant pathogenicity classifications, review status, and disease associations via REST API
• bio-clinical-databases-dbsnp-queriesQuery dbSNP for rsID lookups, variant annotations, and cross-references to other databases. Use when mapping b
• bio-clinical-databases-gnomad-frequenciesQuery gnomAD for population allele frequencies to assess variant rarity. Use when filtering variants by popula
• bio-clinical-databases-hla-typingCall HLA alleles from NGS data using OptiType, HLA-HD, or arcasHLA for immunogenomics applications. Use when d
• bio-clinical-databases-myvariant-queriesQuery myvariant.info API for aggregated variant annotations from multiple databases (ClinVar, gnomAD, dbSNP, C
• bio-clinical-databases-pharmacogenomicsQuery PharmGKB and CPIC for drug-gene interactions, pharmacogenomic annotations, and dosing guidelines. Use wh
• bio-clinical-databases-polygenic-riskCalculate polygenic risk scores using PRSice-2, LDpred2, or PRS-CS from GWAS summary statistics. Use when pred
• bio-clinical-databases-somatic-signaturesExtract and analyze mutational signatures from somatic variants using SigProfiler or MutationalPatterns to cha
• bio-clinical-databases-tumor-mutational-burdenCalculate tumor mutational burden from panel or WES data with proper normalization and clinical thresholds. Us
• bio-clinical-databases-variant-prioritizationFilter and prioritize variants by pathogenicity, population frequency, and clinical evidence for rare disease
• bio-clip-seq-binding-site-annotationThe largest open-source medical AI skills library for OpenClaw🦞.
• bio-clip-seq-clip-alignmentThe largest open-source medical AI skills library for OpenClaw🦞.
• bio-clip-seq-clip-motif-analysisThe largest open-source medical AI skills library for OpenClaw🦞.
• bio-clip-seq-clip-peak-callingThe largest open-source medical AI skills library for OpenClaw🦞.
• bio-clip-seq-clip-preprocessingThe largest open-source medical AI skills library for OpenClaw🦞.
• bio-codon-usageThe largest open-source medical AI skills library for OpenClaw🦞.
• bio-comparative-genomics-ancestral-reconstructionThe largest open-source medical AI skills library for OpenClaw🦞.
• bio-comparative-genomics-hgt-detectionThe largest open-source medical AI skills library for OpenClaw🦞.
• bio-comparative-genomics-ortholog-inferenceThe largest open-source medical AI skills library for OpenClaw🦞.